Molekulare Bioenergetik

Prof. Dr. Ulrich Brandt

Publikationen 2009

Originalpublikationen und Reviews
  1. Hauptmann, S., Scherping, I., Dröse, S., Brandt, U., Schulz, K.L., Jendrach,M., Leuner, K., Eckert, A. and Müller, W.E. (2009) Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice. Neurobiol. Aging 30:1574-1586
  2. Wittig, I. and Schägger, H. (2009) Supramolecular organization of ATP synthase and respiratory chain in mitochondrial membranes. Biochim. Biophys. Acta - Bioenergetics 1787:672-680
  3. Zickermann, V., Kerscher, S., Zwicker, K., Tocilescu, M.A., Radermacher, M. and Brandt, U. (2009) Architecture of complex I and its implications for electron transfer and proton pumping. Biochim. Biophys. Acta - Bioenergetics 1787:574-583
  4. Dröse, S., Hanley, P. and Brandt, U. (2009) Ambivalent effects of diazoxide on mitochondrial ROS production at respiratory chain complexes I and III. Biochim. Biophys. Acta - General Subjects 1790:558-565
  5. Maly, T., Zwicker, K., Cernescu, A., Brandt, U. and Prisner T.F. (2009) New pulsed EPR methods and their application to characterize mitochondrial complex I. Biochim. Biophys. Acta - Bioenergetics 1787:584-592
  6. Zutz, A., Gumpf, A.,Schägger, H. and Tampe,R.(2009) Mitochondrial ABC Proteins in Health and Disease. Biochim. Biophys. Acta - Bioenergetics 1787:681-690
  7. Wenz, T., Hielscher, R.,Hellwig, P.,Schägger, H., Riechers, S. and Hunte,C.(2009) Role of phospholipids in respiratory cytochrome bc1 complex catalysis and supercomplex formation. Biochim. Biophys. Acta - Bioenergetics 1787:609-616
  8. Koepke,J., Olkhova,E., Angerer,H., Müller,H., Peng,G. and Michel,H. (2009) High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase: New insights into the active site and the proton transfer pathways. Biochim. Biophys. Acta - Bioenergetics 1787:635-645
  9. Haendeler, J.,Dröse, S., Büchner, N., Jakob,S., Altschmied, J., Goy, C., Spyridopoulos, I., Zeiher, A.M., Brandt, U. and Dimmeler, S.(2009) Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage. Arterioscl. Thromb. Vasc. Biol. 29:929-935
  10. Ding, M.G., di Rago and J.-P., Trumpower B.L. (2009) Combining inhibitor resistance-conferring mutations in cytochrome b creates conditional synthetic lethality in Saccharomyces cerevisiae. J. Biol. Chem. 284:8478-8485
  11. Nübel, E.,Wittig, I.., Kerscher, S., Brandt, U. and Schägger, S.(2009) Two-dimensional native electrophoretic analysis of respiratory supercomplexes from Yarrowia lipolytica. Proteomics 9:2408-2418
  12. Wumaier,Z., Nübel,E., Wittig,I. and Schägger,H. (2009) Two-dimensional native electrophoresis for fluorescent and functional assays of mitochondrial complexes. Meth. Enzymol. 456:153-168
  13. Dröse,S., Galkin,A. and Brandt,U. (2009) Measurement of superoxide formation by mitochondrial complex I of Yarrowia lipolytica. Meth. Enzymol. 456:475-490
  14. Ding, M.G., Butler,C.A., Saracco,S.A., Fox,T.D., Godard,F., di Rago,J.-P. and Trumpower,B.L. (2009) An Improved Method for Introducing Point Mutations into the Mitochondrial Cytochrome b Gene to Facilitate Studying the Role of Cytochrome b in the Formation of Reactive Oxygen Species. Meth. Enzymol. 456:491-506
  15. Abdel-Rahman, U.,Risteski, P., Tizi, K.,  Kerscher,S.,  Bejati, S.,  Zwicker, K., Scholz, M.,  Brandt,U. and Moritz,A. (2009) Hypoxic reoxygenation during initial reperfusion attenuates cardiac dysfunction and limits ischemia–reperfusion injury after cardioplegic arrest in a porcine model. J. Thorac. Cardiovasc. Sur. 137:978-982
  16. Heide,H., Nordhues,A., Drepper,F., Nick,S., Schulz-Raffelt,M., Haehnel,W. and Schroda,M. (2009) Application of quantitative immunoprecipitation combined with knockdown and cross-linking to Chlamydomonas reveals the presence of vesicle-inducing protein in plastids 1 in a common complex with chloroplast HSP90C. Proteomics 9:3079-3089
  17. Sheftel,A.D., Stehling,O.,Pierik,A.J.,Netz,D.J.A.,Kerscher,S.,Elsässer,H.-P., Wittig,I., Balk,J., Brandt,U. and Lill,R. (2009) Human Ind1, an iron-sulfur cluster assembly factor for respiratory complex I. Mol. Cell. Biol. 29:6059-6073
  18. Rhein,V., Song,X., Wiesner,A., Ittner,L.M., Baysang,G., Meier,F., Ozmen,L., Bluethmann,H., Dröse,S., Brandt,U., Savaskan,E., Czech,C., Götz,J. and Eckert,A. (2009) Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer’s disease mice. Proc. Natl. Acad. Sci. USA 106:20057-20062.
  19. Wittig,I. and Schägger,H. (2009) Native electrophoretic techniques to identify protein-protein interactions. Proteomics 9:5214-5223.

Lehr- und Handbuchbeiträge, Monografien

  1. Burré, J., Wittig, I., and Schägger, H. (2009) Non-classical 2-D electrophoresis. Methods Mol. Biol. 564, 33-57.

Supplements / Abstracts