Institut für Biochemie I (Molekulare Bioenergetik)

Komm. Direktor: Prof. Dr. Ulrich Brandt

Publikationen 2004

Originalpublikationen und Reviews
  1. Stroh, A., Anderka, O., Pfeiffer, K.,  Yagi, T., Finel, M., Ludwig, B. and  Schägger, H. Assembly of respiratory complexes I, III, and IV into NADH oxidase supercomplex stabilizes complex I in Paracoccus denitrificans, Journal of Biological Chemistry (2004) 279(6):5000-5007.

  2. Grgic,L., Zwicker,K., Kashani-Poor,N., Kerscher,S., and Brandt,U. Functional significance of conserved histidines and arginines in the 49 kDa subunit of mitochondrial complex I, Journal of Biological Chemistry (2004) 279(20): 21193 - 21199.

  3. Hamada,T., Ichimaru,N., Abe,M., Fujita,D., Kenmochi,A., Nishioka,T., Zwicker,K., Brandt,U., and Miyoshi,H. Synthesis and Inhibitory Action of Novel Acetogenin Mimics with Bovine Heart Mitochondrial Complex I, Biochemistry (2004) 43(12); 3651-3658

  4. Maly,T., MacMillan,F., Zwicker,K., Kashani-Poor,N., Brandt,U., and Prisner,T.F. Relaxation Filtered Hyperfine (REFINE) Spectroscopy: A Novel Tool for Studying Overlapping Biological Electron Paramagnetic Resonance Signals Applied to Mitochondrial Complex I, Biochemistry (2004) 43(13); 3969-3978

  5. Abdrakhmanova,A., Zickermann,V., Bostina,M., Radermacher,M., Schägger,H., Kerscher,S. and Brandt,U. Subunit Composition of Mitochondrial Complex I from the Yeast Yarrowia lipolytica, Biochim Biophys. Acta - Bioenergetics (2004) 1658:148-156

  6. Schägger,H., de Coo,R., Bauer,M.F., Hofmann,S., Godinot,C., and Brandt, U. Significance of respirasomes for the assembly/stability of human respiratory chain complex I Journal of Biological Chemistry (2004) 279: 36349 - 36353
  7. Rais, I., Karas, M., and Schägger, H. Two-dimensional electrophoresis for the isolation of integral membrane proteins and mass spectrometric identification. Proteomics (2004) 4, 2567-2571

  8. Tziatzios, C., Schubert, D., Lotz, M., Gundogan, D., Betz, H., Schägger, H., Haase, W., Duong, F., and Collinson, I. The bacterial protein-translocation complex: SecYEG dimers associate with one or two SecA molecules  J. Mol. Biol. (2004) 340, 513-524.

  9. Kerscher, S., Grgic, L., Garofano, A. and Brandt, U. Application of the yeast Yarrowia lipolytica as a model to analyse human pathogenic mutations in mitochondrial complex I (NADH:ubiquinone oxidoreductase) Biochim. Biophys. Acta - Bioenergetics  (2004) 1659, 197-205.

  10. Kerscher, S., Bénit, P., Abdrakhmanova, A., Zwicker, K., Rais, I., Karas, M., Rustin,P. and Brandt,U.  Processing of the 24 kDa subunit mitochondrial import signal is not required for assembly of functional complex I in Yarrowia lipolytica. Eur. J. Biochem. (2004) 279, 36349-36353.
  11. Gohil, V.M. , Hayes, P., Matsuyama, S., Schlame, M., Schägger,H., and  Greenberg,M.L. Cardiolipin biosynthesis and mitochondrial respiratory chain function are interdependent Journal of Biological Chemistry (2004)  279: 42612-42618.

  12. Vahsen, N., Candé, C., Brière, J.-J., Bénit, P., Joza, N., Mastroberardino, P.G., Pequignot, M.O., Casares, N., Larochette, N., Métivier, D., Feraud, O., Debili, N., Wissing, S., Engelhardt, S.,  Madeo, F., Piacentini, M., Penninger, J.M., Schägger, H., Rustin, P., and Kroemer, G. AIF deficiency compromises oxidative phosphorylation. EMBO J. (2004) 23, 4679-4689.

  13. Nagel-Wolfrum, K., Buerger, C., Wittig, I., Butz, K., Hoppe-Seyler, F., and Groner, B. The interaction of specific peptide aptamers with the DNA binding domain and the dimerization domain of the transcription factor stat3 inhibits transactivation and induces apoptosis in tumor cells. Molecular Cancer Research (2004) 2(3): 170-82.

  14. Keller, A., Mohamed, A., Dröse, S., Brandt, U., Fleming, I., Brandes, R.P. Analysis of dichlorodihydrofluorescein and dihydrocalcein as probes for the detection of intracellular reactive oxygen species. Free Radical Research (2004) 38, 1257-1267.

Lehr- und Handbuchbeiträge, Monografien

  1. Brandt, U., Respiratory Chain Complex I,  in Encyclopedia of Biological Chemistry (2004) pp676-680, Elsevier Amsterdam, ISBN: 0124437109.

Supplements / Abstracts

  1. Brandt,U., Garofano,A.,  Grgic,L.,   Zickermann,V., Dröse, S., Kerscher, S. Yarrowia lipolytica, a model organism to study mitochondrial complex I by yeast genetics Biochim Biophys. Acta - Bioenergetics (2004) 1657 Supplement, 21

  2. Dröse, S., Tschank,G.,  Lindenschmidt, A., Brandt,U. The glucose uptake stimulators YM-126414 and YM- 138552 are potent uncouplers of the mitochondrial respiration Biochim Biophys. Acta - Bioenergetics (2004) 1657 Supplement, 56

  3. Brandt,U., Garofano,A.,  Grgic,L., Kerscher, S. Application of the yeast Yarrowia lipolytica as a model to analyse human pathogenic mutations Biochim Biophys. Acta - Bioenergetics (2004) 1657 Supplement, 87