Institut für Biochemie I (Molekulare Bioenergetik)

Komm. Direktor: Prof. Dr. Ulrich Brandt

Publikationen 2003

Originalpublikationen und Reviews
  1. Peng,G., Fritzsch,G., Zickermann,V., Schägger,H., Mentele,R., Lottspeich,F., Bostina,M., Radermacher,M., Huber,R., Stetter,K.O., and Michel,H.  Isolation, characterization and electron microscopic single particle analysis of the NADH:ubiquinone oxidoreductase (complex I) from the hyperthermophilic eubacterium aquifex aeolicus. Biochemistry 42(10):3032-3039 (2003). 

  2. Brandt, U., Kerscher, S., Dröse, S., Zwicker, K., and Zickermann, V. Proton pumping by NADH:ubiquinone oxidoreductase. A redox driven conformational change mechanism? FEBS Letters,. 545(1):9-17 (2003).

  3. Schweitzer C., Mehrdad Z., Noll A., Grabner E.W., Schmidt R. Mechanism of photosensitized generation of singlet oxygen during oxygen quenching of triplet states and the general dependence of the rate constants and efficiencies of O-2((1)Sigma(+)(g)), O-2((1)Delta(g)), and O-2((3)Sigma(-)(g)) formation on sensitizer J. Phys. Chem. A, 107(13): 2192-2198 (2003). 

  4. Zickermann, V., Bostina, M., Hunte, C., Ruiz, T., Radermacher, M., and Brandt, U. Functional implications from an unexpected position of the 49 kDa subunit of complex I. Journal of Biological Chemistry, 276:29072-29078 (2003)

  5. Kessl, J.J., Lange, B.B., Merbitz-Zahradnik, T., Zwicker, K., Hill, P., Meunier, B., Hunte, C., Meshnick, S., and Trumpower, B.L. Molecular basis for atovaquone binding to the cytochrome bc1 complex, Journal of Biological Chemistry, 278: 31312-31318 (2003).

  6. Simonnet,H., Demont,J., Pfeiffer,K., Guenaneche, L., Bouvier,R., Brandt, U., Schägger,H., and Godinot,V. Mitochondrial complex I is deficient in renal oncocytomas. Carcinogenesis, 24:1461-1466 (2003). 

  7. Iwaki,M., Giotta,L., Akinsiku,A.O., Schägger,H., Fisher,N., Breton,J., and Rich P.R. Redox-induced transitions in bovine cytochrome bc1 complex studied by perfusion-induced ATR-FTIR spectroscopy. Biochemistry 42:11109-11119 (2003).

  8. Garofano, A., Zwicker, K., Kerscher, S., Okun, P., and Brandt, U. Two aspartic acid residues in the PSST-homologous NUKM subunit of complex I from Yarrowia lipolytica are essential for catalytic activity, Journal of Biological Chemistry, 278: 42435-42440 (2003).

  9. Pfeiffer, K., Gohil, V., Stuart, R.A., Hunte, C., Brandt, U., Greenberg, M.L. and Schägger, H. Cardiolipin stabilizes respiratory chain supercomplexes, Journal of Biological Chemistry, 278: 52873-52880 (2003)

  10. Merbitz-Zahradnik, T., Zwicker, K., Nett, J. H., Link, T. A., Trumpower, B. L. Elimination of the disulfide bridge in the Rieske iron-sulfur protein allows assembly of the [2Fe-2S] cluster into the Rieske protein but damages the ubiquinol oxidation site in the cytochrome bc1 complex, Biochemistry, 42(46):13637-13645 (2003)

  11. Wittmann,V., Seeberger,S., and Schägger,H. Temporary attachment of carbohydrates to cyclopeptide templates: a new strategy for single-bead analysis of multivalent neoglycopeptides, Tetrahedron Letters 44: 9243-9246 (2003)

  12. Schühle,K., Gescher,J., Feil, U., Paul,M., Jahn,M., Schägger,H. and Fuchs,G. Benzoate-conenzyme A ligase from Thauera aromatica:  an enzyme acting in anaerobic and aerobic benzoate pathways, J. Bacteriol. 185, 4920-4929 (2003)

  13. Bénit P., Beugnot R., Chretien D., Giurgea I., de Lonlay-Debeney P., Issartel J.P., Kerscher S., Rustin P., Rötig A., Munnich A. (2003) Mutant NDUFV2 subunit of mitochondrial complex I causes early onset hypertrophic cardiomyopathy and encephalopathy. Hum. Mutat. 21: 582-586.

Lehr- und Handbuchbeiträge, Monografien

  1. Brandt,U. (Hrsg.) Geschichte der Gesellschaft für Biochemie und Molekularbiologie 1947-2002, Spektrum Akademischer Verlag,     Heidelberg (2003)

  2. Hunte,C., von Jagow,G. and Schägger,H. (Eds.) Membrane Protein Purification and Crystallization. A Practical Guide, Second Edition  Academic Press (2003)