Institut für Biochemie I (Molekulare Bioenergetik)

Komm. Direktor: Prof. Dr. Ulrich Brandt

 

Publikationen 2001

Originalpublikationen und Reviews
  1. Kashani-Poor,N., Kerscher,S., Zickermann,V. & Brandt,U. Efficient large scale purification of his-tagged proton-translocating NADH:ubiquinone oxidoreductase (complex I) from the strictly aerobic yeast Yarrowia lipolytica. Biochim. Biophys. Acta - Bioenergetics 1504, 186-193 (2001)

  2. Kerscher,S., Kashani-Poor,N., Zwicker,K., Zickermann,V. & Brandt,U. Exploring the catalytic core of complex I by Yarrowia lipolytica yeast genetics. Journal of Bioenergetics and Biomembranes  33, 187-196 (2001)

  3. Kerscher,S., Durstewitz,G., Casaregola,S., Gaillardin,C. & Brandt,U. The complete mitochondrial genome of Yarrowia lipolytica. Comparative and Functional Genomics 2, 80-90 (2001)

  4. Laempe,D., Jahn,M., Breese,K., Schägger,H. & Fuchs,G. Anaerobic Metabolism of 3-Hydroxybenzoate by the Denitrifying Bacterium Thauera aromatica. J. Bacteriol. 183, 968-979 (2001)

  5. Grüber,G., Svergun,D.I., Coskun,Ü., Lemker,T., Koch,M.H.J., Schägger,H., & Müller,V. Structural Insights into  the A1 ATPase from the Archaeon, Methanosarcina mazei Gö1. Biochemistry 40, 1890-1896 (2001)

  6. Carrozzo,R., Tessa,A., Vázquez-Memije,M.E., Piemonte,F., Patrono,C., Malandrini,A., Dionisi-Vici,C., Vilarinho,L., Villanova,M., Schägger,H., Federico,A., Bertini,E., Santorelli,F.M. The T9176G mtDNA mutation severely affects ATP production and results in Leigh syndrome. Neurology 56, 689-690 (2001)

  7. Kashani-Poor, N., Zwicker,K., Kerscher,S.J. und  Brandt. U.  A central functional role for the 49kDa subunit within the catalytic core of mitochondrial complex I, J. Biol. Chem. 276, 24082-24087 (2001) 

  8. Schägger,H. Blue native gels to isolate protein complexes from mitochondria. Methods in Cell Biology 65, 231-244 (2001)

  9. Dröse S, Boddien C, Gassel M, Ingenhorst G, Zeeck A und Altendorf K. Semisynthetic derivatives of concanamycin A and C, as inhibitors of V- and P-type ATPases: structure-activity investigations and developments of photoaffinity probes. Biochemistry 40, 2816-2825 (2001) 

  10. Ingenhorst, G., Bindseil, K.-U., Boddien,C., Dröse, S., Gaßel, M., Altendorf, K., Zeeck, A. Synthesis of a doubly labelled concanamycin derivative for ATPase binding studies, Eur. J. Org. Chem. 2001, 4525-4532 (2001)

  11. Bartoschek, S., Johansson, M., Geierstanger, B.H., J.G. Okun, Lancaster, C.R.D, Humpfer, E., Yu, C.-A., Griesinger, C. und Brandt, U. Three ubiquinone molecules essential for energy conservation by respiratory cytochrome bc1 complex. J. Biol. Chem, Accelerated Publication 276, 35231-35234 (2001)

  12. Schägger H. und Pfeiffer K. The ratio of oxidative phosphorylation complexes I, II, III, IV, and V in bovine heart mitochondria, and the composition of respiratory chain supercomplexes. J. Biol. Chem.   276, 37861-37867 (2001)

  13. Kerscher,S, Eschemann, A., Okun, P. und Brandt, U. External alternative NADH: ubiquinone oxidoreductase redirected to the inner face of the mitochondrial membrane rescues complex I deficiency in Yarrowia lipolytica, J. Cell Sci. 114, 3915-3921 (2001)

  14. Schägger, H. Respiratory chain supercomplexes, IUBMB-Life 52, 119-128 (2001)

  15. Piemonte, F., Casali, C., Carrozzo, R., Schägger, H., Patrono, C., Tessa, A., Tozzi, G., Cricchi, F., Di Capua, M., Siciliano, G., Amabile, G.A., Morocutti, C., Bertini, E., and Santorelli, F.M. Respiratory chain defects in hereditary spastic paraplegias. Neuromuscular disorders 11, 565-569 (2001)

Lehr- und Handbuchbeiträge, Monografien
  1. Brandt, U. und Zickermann, V. Interaction of ubiquinone and inhibitors with mitochondrial complex I –   implications for the catalytic mechanism, in Mitochondrial Ubiquinone (Coenzyme Q10); Biochemical, Functional, Medical and Therapeutic Aspects in Human Health and Diseases, Vol. 1, Chapter 14, pp 475-488 (Marwah, J., Chopra R.K. and Ebadi, M., Hrsg.), Prominent Press, Scottsdale.

Abstracts
  1. Maly, T., Zwicker, K., Kashani-Poor, N., MacMillan, F., Brandt, U., Prisner, T.F. Direct evidence for the nitrogen ligation of the N2-FeS-Cluster in complex I from Yarrowia lipolytica, J. Inorg. Biochem  86, 327 (2001)