Institut für Biochemie I (Molekulare Bioenergetik)

Komm. Direktor: Prof. Dr. Ulrich Brandt

Publikationen 1997

Originalpublikationen und Reviews
  1. Brandt U: Proton-translocation by membrane-bound NADH:Ubiquinone-oxidoreductase (complex I) through redox-gated ligand conduction. Biochim Biophys Acta 1318: 79-91, 1997.

  2. Brandt U, Djafarzadeh R: Binding of MOA-stilbene to the mitochondrial cytochrome bc1 complex is affected by the protonation state of a redox-Bohr group of the "Rieske" iron-sulfur protein. Biochim Biophys Acta 1321: 238-242, 1997.

  3. Brandt U, Okun JG: Role of deprotonation events in ubihydroquinone:cytochrome c oxidoreductase from bovine heart and yeast mitochondria. Biochemistry 36: 11234-11240, 1997.

  4. Dionisi-Vici C, Ruitenbeek W, Fariello G, Bentlage HACM, Wanders RJA, Schägger H, Piantadosi CA, Sabetta G, Bertini E: New familial mitochondrial encephalopathy with macrocephaly, cardiomyopathy and complex I deficiency. Ann Neurol 42: 661-665, 1997.

  5. Durstewitz G, Terwilliger NB: cDNA cloning of a developmentally regulated hemocyanin subunit in the crustacean Cancer magister and phylogenetic analysis of the hemocyanin gene family. Mol Biol Evol 14:266-276, 1997.

  6. Durstewitz G, Terwilliger NB: Developmental changes in hemocyanin expression in the Dungeness crab, Cancer magister. J Biol Chem 272: 4347-4350, 1997.

  7. Eisinger DP, Dick FA, Denke E, Trumpower BL: SQT1, which encodes an essential WD domain protein of Saccharomyces cerevisiae, suppresses dominant-negative mutations of the ribosomal protein gene QSR1. Mol Cell Biol 17: 5146-5155, 1997.

  8. Engler M, Anke T, Sterner O, Brandt U: Pterulinic acid and pterulone, two novel inhibitors of NADH:ubiquinone oxidoreductase produced by a Pterula species. J Antibiotics 50: 325-329, 1997.

  9. Link TA: The role of the "Rieske" iron sulfur protein in the hydroquinone oxidation (QP) site of the cytochrome bc1 complex - The "proton-gated affinity change" mechanism. FEBS Lett 412: 257-264, 1997.

  10. Müller-Höcker J, Aust D, Rohrbach H, Napiwotzky J, Reith A, Link TA, Seibel P, Hölzel D, Kadenbach B: Defects of the respiratory chain in the normal human liver and in cirrhosis during aging. Hepatology 26: 709-719, 1997.

  11. Nett JH, Denke E, Trumpower BL: Two-step processing is not essential for the import and assembly of functionally active iron-sulfur protein into the cytochrome bc1 complex in Saccharomyces cerevisiae. J Biol Chem 272: 2212-2217, 1997.

  12. Ortwein C, Link TA, Meunier B, Colson A-M, Rich PR, Brandt U: Structural and functional analysis of deficient mutants in subunit I of cytochrome c oxidase from Saccharomyces cerevisiae. Biochim Biophys Acta 1321: 79-92, 1997.

  13. Rubio-Gozalbo ME, Ruitenbeek W, Bentlage HACM, Schägger H, Sengers RCA, Trijbels JMF, ter Laak HJ, Mariman ECM, Bakker MM, de Jager J, Smeitink IAM: Favourable clinical course in an infant with severe deficiency of complexes I, II and IV. Euro J Pediatr 156: 931-934, 1997.

  14. Schmidt CL, Hatzfeld OM, Petersen A, Link TA, Schäfer G: Expression of the Sulfolobus acidocaldarius Rieske iron sulfur protein II (SOXF) with the correctly inserted [2FE-2S] cluster in Escherichia coli. Biochem Biophys Res Commun 234: 283-287, 1997.

  15. Soppa J, Link TA: The TATA-box-binding protein (TBP) of Halobacterium salinarum. Cloning of the tbp gene, heterologous production of TBP and folding of TBP into a native conformation. Eur J Biochem 249: 318-324, 1997.

  16. Zell R, Geck P, Werdan K, Boekstengers P: TNF-a and IL-1a inhibit both pyruvate dehydrogenase activity and mitochondrial function in cardiomyocytes: Evidence for primary impairment of mitochondrial function. Mol Cell Biochem 177: 61-67, 1997.

  17. Zickermann I, Tautu OS, Link TA, Korn M, Ludwig B, Richter O-MH: Expression studies on the ba3 quinol oxidase from Paracoccus denitrificans. A bb3 variant is enzymatically inactive. Eur J Biochem 246: 618-624, 1997.

 
Lehr- und Handbuchbeiträge, Monografien
  1. Link TA, Hatzfeld OM, Saynovits M: Structure of the "Rieske" iron-sulfur protein of the cytochrome bc1 complex from bovine heart mitochondria studied by electrochemistry, spectroscopy, and crystallography. In: Bioinorganic chemistry - Transition metals in biology and their coordination chemistry. Trautwein AX (Hrsg.), Wiley-VCH, Weinheim: 312-325, 1997.

  2. von Jagow G, Geier BM, Link TA: The mammalian mitochondrial respiratory chain. In: Bioenergetics. Gräber P, Milazzo G (Hrsg.), Birkhäuser Verlag, Basel/Switzerland: 273-309, 1997.

 
Abstracts
  1. Link TA, Saynovits M, Iwata S, Michel H: Structure of the "Rieske" protein: a [2Fe-2S] cluster with histidine coordination. FASEB J 11: A1279, 1997.